How Mark Cuban is Turning the Prescription Drug Industry Upside Down

When Mark Cuban enters an industry, he typically disrupts it in one way or another. And that’s precisely what it appears he has done once again, though this time in the healthcare space. His Cost Plus Drug Company has turned the industry on its head and introduced transparency to the previously opaque area of prescription drug prices.

“We started [Mark Cuban Cost Plus Drug Company] with the goal of being the low-cost provider for generic drugs,” Cuban told MarketScale. 

The company’s website features a chart displaying the stark difference in the retail price of these drugs versus what consumers pay through their platform. But perhaps the most striking thing about the Cost Plus Drug Company is the clarity of the pricing structure. Leadership has been vocal, on the site and on social media, about how Cost Plus Drugs gets to its final prices in an effort to set a new standard for patient-focused transparency.

For example, every drug is priced with the same markups: a 15% markup supports operations, a $3 charge covers pharmacy labor, and then the usual fixed and variable costs of shipping round out the total. Some savings are minimal; a 60-count of 20mg Fluoxetine, the generic alternative for depression and OCD treatment drug Prozac, costs $4.80 for a Cost Plus Drugs customer, compared to the retail price of $43.80.

Some savings are so stark that they warrant a double take. For a 30-count of 400mg Imatinib, the generic version of leukemia-treatment drug Gleevec, Cost Plus Drugs customers pay $47.50, compared to the retail price of $9,657.40, an enormous difference in cost.

“We will do whatever it takes to get affordable pharmaceuticals to patients,” said Alex Oshmyansky, CEO of Mark Cuban Cost Plus Drug. “The markup on potentially lifesaving drugs that people depend on is a problem that can’t be ignored. It is imperative that we take action and help expand access to these medications for those who need them most.”

With this cost savings business model, underinsured or uninsured patients who’d be paying close to or full price would see the most immediate benefits. Even insured patients though, according to the company’s site, would pay “less than what you would pay when using your insurance at a typical pharmacy.”

The cost of drugs in the United States has been a problem for some time, garnering attention from President Biden and putting a financial strain on many Americans. According to Kevin Stevenson, Director of Strategic Operations at Providence Healthcare Network in Waco, TX, affecting positive change in this side of the industry is critical, as for patients, it’s truly a life or death situation.

“People who don’t have insurance that are paying out of pocket, oftentimes they skip medications because they take food out of their family’s mouth,” Stevenson said.

The high-profile attention that Cuban’s company, as well as the issue at-large, is getting could be a sign of things to come for healthcare in the United States.

“I think we’re seeing people in healthcare now that are having that more entrepreneurial mindset, that are looking at problems and saying how can we look at it from a different viewpoint to try to solve this,” he said.

Stevenson admitted that change in healthcare can come slowly, but with sharks like Mark Cuban in the water, change could be coming sooner rather than later. 

Follow us on social media for the latest updates in B2B!

Image

Latest

workforce
How McDonald’s and Skilltrade Are Transforming Workforce Education for America’s Frontline Employees
October 9, 2025

Work is changing fast. Automation and artificial intelligence aren’t just reshaping how we work—they’re redefining who gets access to opportunity in the first place. With frontline workers making up a significant share of the American workforce—and one in eight Americans having worked at McDonald’s—the discussion about education, skills, and upward mobility feels more urgent than…

Read More
Career
How to Build a Purpose-Driven Career in the Age of AI and Acceleration
October 9, 2025

In a world reshaped by AI, global connectivity, and relentless technological advancement, the pace of disruption has never been greater. Careers are being reinvented as industries transform, and individuals everywhere are being challenged to find meaning, adaptability, and creativity in their professional paths. According to Deloitte’s 2024 Gen Z and Millennial Survey, 86% of…

Read More
youth
Fashion, Identity, and Digital Life Collide: Why Brands Must Listen, Collaborate, and Co-Create With the Next Generation of Youth
October 8, 2025

As the lines blur between fashion, identity, and digital life, brands are racing to understand how today’s youth are reshaping culture and commerce. Pacsun’s new Youth Report 2025, produced in partnership with GlobalData, offers one of the most detailed portraits yet of Gen Z and Gen Alpha—two generations united by self-expression but divided by…

Read More
talent
Grow Your Own Talent: How McDonald’s and Skilltrade Are Building a Culture of Lifelong Learning
October 7, 2025

The world of work is changing faster than ever. Automation is reshaping jobs, new technologies are rewriting what “qualified” means, and a new generation of workers is redefining what they expect from employers. From fast food to healthcare, companies are realizing they can’t just hire talent — they have to build it. They’re starting to…

Read More