Dig Your Heels In – Season 2

Dig Your Heels In: A Working Women’s Series with Megan MacDonald

We’ve all had moments when we feel doubt in ourselves, education, experience, and accomplishments. This is known as imposter syndrome, and unfortunately, many female leaders and professional women struggle with imposter syndrome. Megan MacDonald is now a C-Suite executive at Hello Alice, and with solid mentorship, she developed faith in herself. MacDonald’s background focused on…

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Dig Your Heels In - Season 2
Dig Your Heels In: A Working Woman’s Series with YiDing Yu

YiDing Yu is the CMO at Olive, a practicing physician, published researcher, and serial entrepreneur. As a female in the healthcare and tech industries, she’s excited about the growth of women in healthcare. Yu said she grew up with a ton of interests. She knew she wanted to be a doctor when she was little….

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Architecture & Design
Dig Your Heels In: A Working Woman’s Series with Rachel Neill

As any parent knows, keeping kids occupied without using technology can prove to be quite challenging. Screen time continues to be on the rise with the increase in computers and smartphones replacing textbooks in the classroom. The global pandemic brought this to a head with quarantines and school closures necessitating the use of technology to…

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Dig Your Heels In - Season 2
Dig Your Heels In: A Working Woman’s Series with Amy Czuchlewski

Amy Czuchlewski grew up around tech. Her father was an engineer, and her brothers and sister followed in his footsteps. After a high school aptitude test pushed her to study Computer Engineering at the University of Michigan, it was a total surprise to her that women were in the minority. “It hadn’t occurred to me…

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Dig Your Heels In - Season 2
Dig Your Heels In: A Working Woman’s Series with Jolene Delisle

A captivating story is often vital in building a successful business. Jolene Delisle, Founder and Head Creative at The Working Assembly, a branding and creative industry for clients at various life stages, recognized the need for brands to refine, synthesize, and market themselves throughout their life cycles using storytelling. Delisle sits down with host Gabrielle…

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vitro
Analyzing the Suppressive TME in In Vitro Based Assays
April 19, 2025

In the rapidly advancing field of cancer immunotherapy, accurately modeling the tumor microenvironment (TME) has become essential to improving the predictive power of preclinical drug testing. As immune-modulating therapies surge forward, with over 4,000 immune modulators in development globally, scientists are refining assay technologies that maintain the complexity of patient-specific tumor biology. In vitro platforms…

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cancer
Targeting T Cells Within the Cancer Immunity Cycle
April 19, 2025

As cancer immunotherapy continues to reshape treatment landscapes, fine-tuning T-cell responses has become a critical frontier. Recent advances in 3D organoid models and high-content imaging are enabling scientists to closely mimic patient-specific tumor environments—unlocking insights into how T cells behave, respond, and falter under immune checkpoint blockade. With over 4,000 immune modulators in clinical…

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cancer Immunity cycle
Advanced In Vitro Technologies to Investigate Therapeutic Impact on the Cancer Immunity Cycle
April 19, 2025

As immunotherapy revolutionizes cancer treatment, the need for physiologically relevant preclinical models becomes more urgent than ever. Despite the success of immune checkpoint inhibitors, a large majority of patients fail to achieve long-lasting responses, prompting researchers to explore more complex and predictive assays. The cancer immunity cycle, first described in 2013, remains a central framework…

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resistance
Inside Oncology Drug Development: Overcoming Resistance with Science
April 19, 2025

In the last two decades, oncology has undergone a transformation with over 300 new cancer therapies approved by the FDA—many offering novel mechanisms of action. Despite these innovations, resistance to treatment remains a critical challenge, with cancer cells evolving or adapting to evade even the most advanced therapeutics. This issue is particularly pressing given that…

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