Engineering Experience
During the COVID-19 pandemic, Paragon Innovations, under the leadership of Mike Wilkinson, exhibited remarkable resilience and innovation. They saw the market downturn as an opportunity to reimagine their strategies and adapt accordingly. With a seamless transition to remote work, Paragon Innovations ensured uninterrupted service to their clients. Leveraging technology, they provided their customers with advanced…
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Engineering & Construction
Navigating the Semiconductor Chip Shortage
Joe Piccirilli, Founder and CEO of RoseWater Energy Group, and Mike Wilkinson, Founder, General Manager, and Vice President of Paragon Innovations, joined forces for a special combined episode of their respective podcasts’ Engineering Experience and The Next Generation of Energy to address the ongoing semiconductor chip shortage impacting their industry. Wilkinson wasn’t going to sugarcoat…
Engineering Experience
All Things IoT
The IoT ecosystem is accelerating, with innovation moving forward rapidly. It has applications in many industries, and those use cases will be at the forefront of the 2021 Works With Conference hosted by Silicon Labs. On Engineering Experience, host Tyler Kern spoke with Keith Nesrsta, Regional Sales Manager at Silicon Labs, and Paragon Innovations…
Engineering & Construction
Contemporary Looks at Classic Designs Can Spur New Life in Engineering
On this episode of Engineering Experience by Paragon Innovations, host Tyler Kern talked with Brewster Waddell, CEO of TH Waddell Designs, Bob Landers, VP of Engineering at TH Waddell Designs, and Mike Wilkinson, Founder and CEO of Paragon Innovations. The group talked about an invention by Waddell’s father, Theodore. The table lamps designed by Theodore…
Engineering & Construction
Engineering Experience: Technology’s Role in the Future of Banking
Engineering can involve any industry, and Engineering Experience is all about bringing those unique stories to listeners. Host Tyler Kern and Paragon CEO Mike Wilkinson spoke with Chris Debrecht, Owner and COO of Tempo Financial Solutions, about his company’s partnership with Paragon. Tempo specializes in hardware and software for cash automation, serving big and small…
Engineering & Construction
Bringing IoT Solutions to the Great Outdoors
Ray Dikun, Director of Technology at Plano Synergy, has a career in telecom that’s taken him around the globe throughout the past 30 years. From Motorola to RIM, Dikun’s seen the digital evolution up close and is one of its creators. Dikun joined Mike Wilkinson, Founder and CEO of Paragon Innovations, and host Tyler Kern…
Engineering Experience
Works With Virtual Conference on September 9-10, 2020
Calling all engineers: The Works With Virtual Conference by Silicon Labs happens September 9-10, 2020. This free virtual event will bring together industry leaders, hardware engineers, application designers and developers for the largest smart home event dedicated to integrating smart home application designs with any hub or smart home ecosystem. Keith Nesrsta, South-Central Regional Sales…
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Analyzing the Suppressive TME in In Vitro Based Assays
In the rapidly advancing field of cancer immunotherapy, accurately modeling the tumor microenvironment (TME) has become essential to improving the predictive power of preclinical drug testing. As immune-modulating therapies surge forward, with over 4,000 immune modulators in development globally, scientists are refining assay technologies that maintain the complexity of patient-specific tumor biology. In vitro platforms…
Targeting T Cells Within the Cancer Immunity Cycle
As cancer immunotherapy continues to reshape treatment landscapes, fine-tuning T-cell responses has become a critical frontier. Recent advances in 3D organoid models and high-content imaging are enabling scientists to closely mimic patient-specific tumor environments—unlocking insights into how T cells behave, respond, and falter under immune checkpoint blockade. With over 4,000 immune modulators in clinical…
Advanced In Vitro Technologies to Investigate Therapeutic Impact on the Cancer Immunity Cycle
As immunotherapy revolutionizes cancer treatment, the need for physiologically relevant preclinical models becomes more urgent than ever. Despite the success of immune checkpoint inhibitors, a large majority of patients fail to achieve long-lasting responses, prompting researchers to explore more complex and predictive assays. The cancer immunity cycle, first described in 2013, remains a central framework…
Inside Oncology Drug Development: Overcoming Resistance with Science
In the last two decades, oncology has undergone a transformation with over 300 new cancer therapies approved by the FDA—many offering novel mechanisms of action. Despite these innovations, resistance to treatment remains a critical challenge, with cancer cells evolving or adapting to evade even the most advanced therapeutics. This issue is particularly pressing given that…